Although Clapton has varied his musical style throughout his career, it has always remained grounded in the blues. Yet, in spite of this focus, he is credited as an innovator in a wide variety of genres. These include blues-rock (with John Mayall & the Bluesbreakers and the Yardbirds) and psychedelic rock (with Cream). Additionally, Clapton's chart success was not limited to the blues, with chart-toppers in Delta Blues (Me and Mr. Johnson), pop ("Change the World") and reggae (Bob Marley's "I Shot the Sheriff"). One of his most successful recordings was the hit love song "Layla," which he played with the band Derek and the Dominos.